Siddhartha Thakur

Bio

Dr. Siddhartha “Sid” Thakur is a Professor in the College of Veterinary Medicine at North Carolina State University. He is the Director of Global Health program at both the College of Veterinary Medicine and the NC State University. He was the Associate Director at the Comparative Medicine Institute and led the Emerging and Infectious Diseases Research program. He received his Degree in Veterinary Medicine and Master of Veterinary Public Health from India. He earned his Ph.D. in Population Medicine at the College of Veterinary Medicine, NC State. Before joining the faculty at NC State University, Dr. Thakur was an Oakridge Research Fellow at Center for Veterinary Medicine, FDA, Maryland. He espouses the concepts of “One Health” and seeks to understand how antimicrobial resistance develops in “superbugs” that affect animal and human health. He has won numerous awards including the Larry Beuchat Young Researcher Award by the International Association for Food and the Outstanding Global Engagement award by NC State. He is currently an NC State Chancellor faculty scholar. Dr. Thakur has authored or co-authored 45 peer-reviewed publications and edited two books.

Affiliations

American Society for Microbiology
International Association for Food Protection
Duke One Health, https://sites.globalhealth.duke.edu/dukeonehealth/

Area(s) of Expertise

Dr. Thakur`s research is centered on two predominant themes. The first revolves around understanding the phenotypic and genotypic similarity and/or diversity of AMR bacterial strains reported in animals and humans. This involves characterizing and elucidating the mechanisms of AMR at the molecular level, analyzing DNA fingerprint patterns, and determining the risk factors that predispose animals and humans to infections by these strains. The second theme focuses on using phylogenetics to study the evolution of drug-resistant bacterial strains at the population level. In this, molecular approaches are undertaken to analyze pathogen evolution on an evolutionary scale.

Publications

• Comparison of PCR and culture for detection of Campylobacter jejuni in canine feces , Journal of Veterinary Diagnostic Investigation (2026)
• Genomic determinants of fluoroquinolone resistance in Escherichia coli in Nigeria: dominance of QRDR mutations and limited contribution of PMQR in a cross-sectional study , BMC Medical Genomics (2026)
• Inter-laboratory optimization for the detection of Campylobacter jejuni in canine fecal samples using gyrA PCR , Journal of Veterinary Diagnostic Investigation (2026)
• One Health transmission of plasmid-mediated antimicrobial resistance: genomic insights at the interface of food, animals, humans and the environment , JAC-Antimicrobial Resistance (2026)
• Clonal spread of blaCTX-M-65 producing Salmonella enterica serovars detected in poultry retail meat in North Carolina, USA , Scientific Reports (2025)
• How does one health fit into current academic frameworks? Insights from a SWOT analysis by the North America One Health University Network , Frontiers in Medicine (2025)
• Risk factors for fluoroquinolone- and macrolide-resistance among swine Campylobacter coli using multi-layered chain graphs , PLoS Computational Biology (2025)
• Whole genome sequencing reveals virulence–mobile element linkages and phylogenetic diversity in multidrug-resistant Escherichia coli from Nigeria , Frontiers in Microbiology (2025)
• Antimicrobial resistance in food-borne pathogens at the human-animal interface: Results from a large surveillance study in India , One Health (2024)
• Can a One Health approach be a roadmap to reduce salmonellosis? , International Association for Food Protection Annual Meeting (2024)