Research in the Lyu lab encompasses anaerobic and molecular microbiology, microbial
\nphysiology and metabolism, and microbial ecology and evolution. We are particularly interested
\nin employing live microbes inclusive of both archaea and bacteria as model systems to broadly
\nstudy the functional roles of oxygen-sensitive microbes across multiple settings such as human
\nand animal health, agriculture, climate change, and biotechnology. To accomplish our research
\ngoals, we aspire to 1) establish and integrate cultivation-dependent and -independent
\napproaches to define physiology-relevant microbial phenotypes at the community, population,
\norganismal or molecular levels; 2) develop and apply genetic, biochemical, and omic methods in
\nvitro and in vivo to mechanistically characterize the observed phenotypes; and 3) bring and
\ntranslate new findings into tangible solutions by harnessing the cross-boundary power of
\nmicrobes.
\nOur current projects focus on:
\n\u2013 Microbiome and host health
\n\u2013 Methanogenic archaea and methanogenesis
\n\u2013 Archaea-bacterial interactions<\/p>\n